Year: 2018
Pages: 344-350
Number: Volume 10, issue 4
Type: scientific article
DOI: https://doi.org/10.31301/2221-6197.bmcs.2019-44
Topic: Article
Authors: Mindubaev A.Z.!, Babynin E.V.!, Badeeva E.K.!, Minzanova S.T.!, Voloshina A.D.!, Piskunov D.B.!, Makhiyanov A.N.!, Mironova L.G.!
In the present study the genotoxicity of white phosphorus is evaluated using the Ames test, which demonstrated the absence of toxicity. In the present work SOS-lux test has demonstrated genotoxicity. This result is obtained for the first time – all the available literature sources reported no genotoxic properties of this substance. For this purpose, an Allium test is used on onion rootlets (Allium cepa L.). In this work, we present the first report on the negative effect of white phosphorus on the cell cycle of eukaryotes by the Allium test method. It turned out that white phosphorus, even at very low concentrations of 0.01%, exponentially increases the number of chromosomal aberrations.
white phosphorus, genotoxicity