Biomics

The methods of chemical immobilization of oligonucleotides on the surface of solid supports used in DNA microarrays production are reviewed. The main attention is paid for the schemes of oligonucleotides covalent grafting to the glass surface. The techniques for spatial ordering and dilution of oligonucleotide molecules on the surface are considered.

DNA microarrays, oligonucleotides, support, surface functionalization, single anchor immobilization, multiple anchor immobilization

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