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  9. CRISPR/Cas редактирование геномов растений

CRISPR/Cas редактирование геномов растений

Год: 2017

Страницы: 155-182

Номер: Том 9, №3

Тип: научная статья

Рубрика: Статьи

Авторы: Кулуев Булат Разяпович, Геращенков Григорий Алексеевич, Рожнова Н.А.!, Баймиев Андрей Ханифович, Вершинина Зиля Рифовна, Князев Алексей Викторович, Матниязов Рустам Тахирович, Гумерова (Ясыбаева) Гульнар Рафиловна, Михайлова Елена Владимировна, Никоноров Юрий Михайлович, Чемерис Дмитрий Алексеевич, Баймиев Алексей Ханифович, Чемерис Алексей Викторович

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Аннотация:

Описана краткая история и предыстория изучения CRISPR/Cas систем, приведена терминология, показано разнообразие CRISPR/Cas систем, а также различные улучшения технологии геномного редактирования. Проведен наукометрический анализ публикаций в этой области. Приведены примеры редактирования геномов ряда видов растений. Список цитированной литературы составил более 250 наименований и при этом большинство работ опубликованы в последние два-три-четыре года, и лишь немногочисленные статьи, имеющие отношение к истории и предыстории CRISPR/Cas технологии, датированы более ранними годами.

Ключевые слова:

CRISPR, Cas9, Cpf1, nCas9, PAM, NHEJ, HDR, нуклеаза, никаза, двуцепочечные разрывы, крРНК, тракрРНК, гидРНК, спейсер, протоспейсер, нокаут, нокин

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eISSN: 2221-6197 DOI: 10.31301/2221-6197