eISSN: 2221-6197 DOI: 10.31301/2221-6197

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  9. The effect of the maize gene Mtl/Nld/Pla1, Dmp7/Duf679, Bbm1 mutations on the 3D protein models conformations

The effect of the maize gene Mtl/Nld/Pla1, Dmp7/Duf679, Bbm1 mutations on the 3D protein models conformations

Year: 2024

Pages: 260-266

Number: Volume 16, no. 3

Type: scientific article

DOI: https://doi.org/10.31301/2221-6197.bmcs.2024-16

Topic: Articles

Authors: Fadeev, Vladimir, Moiseeva, Yelyzaveta M.

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Summary:

The article presents an analysis of the 3D models for maize (Zea mays L.) gynogenesis proteins (MTL/NLD/PLA1, DMP7/DUF679, BBM1) with spontaneous mutations in the nucleotide sequences of their coding genes. It was found that the four-nucleotides insertion into the Zm_Mtl/Nld/Pla1 gene sequence of haploid-inducing Stock 6 maize line changes the amino acid composition of the β-fold and leads to the replacement of two α-helices with an unstructured section. A single nucleotide substitution of the Dmp7/Duf679 gene in the haploid-inducing CAU5 maize line leads to a change in the α-helix position and the 3D model protein DMP8/DUF679 conformation. On the other hand, the single nucleotide substitutions in the Zm_Bbm1 gene in AT-4 maize line do not lead to a change in the amino acid composition and conformation of the BBM1 protein. 

Keywords:

gynogenesis genes, Mtl/Nld/Pla1, Dmp7/Duf679, Bbm1, maize, mutations, 3D protein models, AlphaFold 3

References:

  1. Abramson J., Adler J., Dunger J. <…>Jaderberg M., Hassabis D., Jumper J. M. Accurate structure prediction of biomolecular interactions with AlphaFold 3. Nature. 2024. V.630. P. 493–500. https://doi.org/10.1038/s41586-024-07487-w
  2. Boutilier K., Offringa R., Sharma V., Kieft H., Ouellet T., Zhang L., Hattori J., Liu C., van Lammeren A. M., Miki L. A., Custers B. M., van Lookeren Campagne M. Ectopic expression of BABY BOOM triggers a conversion from vegetative to embryonic growth. Plant Cell. 2002. V. 14(8). P. 1737–1749. doi: 10.1105/tpc.001941
  3. Chase S.S. Monoploid frequencies in a commercial double cross hybrid maize, and its component single cross hybrids and inbred lines. Genetics. 1949. V. 34. P. 328–332. doi: 10.1093/genetics/34.3.328
  4. Chumakov M.I., Mazilov S. I. Genetic control of gynogenesis in maize (review). Russian J. Genetics. 2022. V. 58(4). P. 384–392.). doi:10.1134/S1022795422040044
  5. Coe E.H. A line of maize with high haploid frequency. American Naturalist. 1959. V. 59. P. 381–382. doi: 10.1086/282098
  6. Conner J.A., Mookkan M., Huo H., Ozias-Akins P. A. A parthenogenesis gene of apomict origin elicits embryo formation from unfertilized eggs in a sexual plant. Proc. Natl. Acad. Sci. USA. 2015. V.112(36). P. 11205–11210. doi: 10.1073/pnas.1505856112
  7. Conner J.A., Podio M., Ozias-Akins P. Haploid embryo production in rice and maize induced by PsASGR-BBML transgenes. Plant Reprod. 2017. V. 30(1). P. 41–52. doi: 10.1007/s00497-017-0298-x
  8. Enaleeva N.Kh., Tyrnov V.S., Selivanova L.P., Zavalishina A.N. Odinarnoe oplodotvorenie i problema gaploinduktsii u kukuruzy. Dokl. Akad. Nauk. SSSR. 1997. V. 353. P. 405–407. [Single fertilization and the problem of haploid induction in maize] (In Russian)
  9. Florez S.L., Erwin R.L., Maximova S.N., Guiltinan M.J., Curtis W.R. Enhanced somatic embryogenesis in Theobroma cacao using the homologous BABY BOOM transcription factor. BMC Plant Biol. 2015. V. 15. P. 121. doi: 10.1186/s12870- 015-0479-4
  10. Gilles L.M., Calhau A.R.M., La Padula V., Jacquier N.M.A., Lionnet C., Martinant J.P., Rogowsky P.M., Widiez T. Lipid anchoring and electrostatic interactions target NOT-LIKE-DAD to pollen endoplasma membrane. J. Cell Biol. 2021. V. 220. e202010077. doi: 10.1083/jcb.202010077
  11. Gilles L.M., Khaled A., Laffaire J.B., Chaignon S., Gendrot G., Bergès H., Beydon G., Bayle V., Barret P., Comadran J., Martinant J., Rogowsky P., Widiez T. Loss of pollen-specific phospholipase NOT LIKE DAD triggers gynogenesis in maize. EMBO J. 2017. V. 36. P. 707–717. doi: 10.15252/embj.201796603
  12. Heidmann I., De Lange B., Lambalk J., Angenent G.C., Boutilier K. Efficient sweet pepper transformation mediated by the BABY BOOM transcription factor. Plant Cell Rep. 2011. V. 30. P. 1107–1115. doi: 10.1007/s00299-011-1018-x
  13. Kelliher T., Starr D., Richbourg L., Chintamanani S., Delzer B., Nuccio M., Green J., Chen Z., McCuiston J., Wang W. MATRILINEAL, a spermspecific phospholipase, triggers maize haploid induction. Nature. 2017. V. 542. P. 105–109. doi: 10.1038/nature20827
  14. Liu C., Li X., Meng D., Zhong Y., Chen C., Qi X., Tian X., Zhang D., Li W., Jiao Y., Zhao H., Song W., Luo M., Xu R., Li J., Liang Q., Zhang M., Lai J., Han B., Li J. A 4-bp insertion at ZmPLA1 encoding a putative phospholipase A generates haploid induction in maize. Mol. Plant. 2017. V. 10. P. 520–522. doi: 10.1016/j.molp.2017.01.011
  15. Luo M., Bilodeau P., Koltunow A., Dennis E.S., Peacock W.J., Chaudhury A.M. Genes controlling fertilization-independent seed development in Arabidopsis thaliana. Proc. Natl. Acad. Sci. USA. 1999. V. 96(1). P. 296–301. doi: 10.1073/pnas.96.1.296
  16. Moiseeva E. M., Fadeev V. V., Fadeeva Yu. V., Mazilov S. I., Chumakov M. I. Comparative analysis of maize gynogenesis gene mutation. Russian J. Genetics. 2024. V. 60(10). P. 1333–1340. DOI: 10.1134/S102279542470087X
  17. Takahashi T., Mori T., Ueda K., Yamada L., Nagahara S., Higashiyama T., Sawada H., Igawa T. The male gamete membrane protein DMP8/DUF6799/DAU2 is required for double fertilization in flowering plants. Development. 2018. V. 145. Iss. 23. P. dev170076. doi: 10.1242/dev.170076
  18. Tyrnov V.S., Zavalishina A.N. Induktsiya vysokoy chastoty vozniknoveniya matroklinnykh gaploidov kukuruzy. Dokl. Akad. Nauk. SSSR. 1984. V. 276. P. 735–738. [Induction of high frequency of matroclinous haploids in maize] (In Russian)
  19. Xu X., Li L., Dong X., Jin W., Melchinger A.E., Chen S. Gametophytic and zygotic selection leads to segregation distortion through in vivo induction of a maternal haploid in maize. J. Exp. Bot. 2013. V. 64. P. 1083–1096. doi: 10.1093/jxb/ers393
  20. Zhong Y., Liu C., Qi X., Jiao Y., Wang D., Wang Y., Liu Z., Chen C., Chen B., Tian X., Li J., Chen M., Dong X., Xu X., Li L., Li W., Liu W., Jin W., Lai J., Chen S. Mutation of ZmDMP8/DUF679 enhances haploid induction in maize. Nature Plants. 2019. V. 5. P. 575–580. doi: 10.1038/s41477-019-0443-7
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eISSN: 2221-6197 DOI: 10.31301/2221-6197