Biomics

The complex of probiotic bacteria Bacillus subtilis contained in the preparation "Apivrach" shows antagonistic activity against the fungus Ascosphaera apis, suppressing its growth by 50 % at a concentration of 15 µl. The drug has a strong competition Bacillus subtilis with pathogenic E. coli and less pronounced – with pathogenic Staphylococcus. When processing the surface of the hive at an exposure of 2 h, the drug does not have a significant effect on non-pathogenic bacilli present on the inner surface of the hive.

«Apivrach», Ascosphaera apis, Bacillus subtilis, pathogens

1. Barmina I.E., Mannapov A.G., Karpova G.V. Stimuliruyushchie podkormki dlya pchelinyh semej s dobavleniem kompleksnyh aminokislotnyh i probioticheskih preparatov. Bulletin of OSU. Orenburg. №12(131). (For stimulating feeding of bee colonies with the addition of a complex amino acid and probiotic preparations) [In Russian].
2. Chausova E.V., Holodnaya L.S., Levchenko I.A. Podkormka dlya pchel: EN 1822689 WITH А01К53/00/ applicant Kiev state University by T. G. Shevchenko (SU), Ukrainian Scientific-Research Technological Institute of Beekeeping (SU), SU 19914928524. No. 4928524/15; application. 18.10.1991; publ. 23.06.1993. (Feeding for bees) [In Russian].
3. Lyapunov YA.E., Kuzyaev R.Z., Hismatullin R.G., Bezgodova O.A. Enterobakterii kishechnika zimuyushchih pchel Apis Mellifera. 2008. V 77. № 3. P. 421–427. (Intestinal enterobacteria of the hibernating Apis Mellifera bees) [In Russian]
4. Nozdrin G.A., Plahova A.A., Kashkovskij V.G. Sposob profilaktiki virusnyh zabolevanij pchel i povysheniya ih produktivnosti: № 2388219 Grew. Federation: A01K47/00 /; applicant and patent holder Novosibirsk state agrarian University. – declared.6.05.2008; publ.10.05.2010. (Method of prevention of viral diseases of bees and increase their productivity) [In Russian].
5. Poltorzhickaya R.S. Ocenka effektivnosti ispol'zovaniya zhivyh probioticheskih preparatov pri mono- i associirovannoj gnil'covo-mikoznoj patologii pchel. Epizootology, Immunobiology, pharmacology and sanitation: international scientific and practical journal. 2009. No. 4. (Evaluation of the effectiveness of the use of live probiotic drugs in mono-and associated rot-mycotic pathology of bees) [In Russian].
6. Poltorzhickaya R.S., CHernik M.I., Beznos T.V., Lemish N.A., YAkubovskij S.M. Probioticheskij potencial bakterij roda Bacillus dlya zashchity pchelinogo gnezda ot patogenov. Epizootology, Immunobiology, pharmacology and sanitation: international scientific and practical journal. 2010. No. 6. (Probiotic potential of bacteria of the genus Bacillus to protect the bee nest from pathogens) [In Russian].
7. Tuktarov V.R., Kuznecova T.N., Mishukovskaya G.S. i dr. Sredstvo dlya stimulyacii fiziologicheskih funkcij u pchel i zashchity ih ot infekcionnyh zabolevanij. The patent for the invention 2380406. – 27.01.2010. (Means for stimulation of physiological functions in bees and their protection from infectious diseases) [In Russian].