Year: 2016
Pages: 239-245
Number: Volume 8, issue 3
Type: scientific article
The review aimed to complete the picture of usage the model species of insects in aging studies. The central object of review is Musca domestica L., house fly. All data will be engaged to application of house fly in the numerous investigations in accordance some problems, important for gerontology:
1) Investigation of the determinants of intrapopulation polymorphism by complex of fitness indices, first of all the life span.
2) Search for effective biomarkers of senescence.
3) Reveal of physiological and genetic mechanisms of action for pharmacological preparations delaying senescence.
4) Investigations of environmental impact on life span, mostly effects of food quality and availability, light and photoperiodic regime, different stressors.
5) Development of models for analysis of certain genetic systems role in manifestation of age-related human diseases
Musca domestica L., house fly, aging, gerontology, fitness, life span