eISSN: 2221-6197 DOI: 10.31301/2221-6197

House fly as a model system for aging studies

Year: 2016

Pages: 239-245

Number: Volume 8, issue 3

Type: scientific article

Summary:

The review aimed to complete the picture of usage the model species of insects in aging studies. The central object of review is Musca domestica L., house fly. All data will be engaged to application of house fly in the numerous investigations in accordance some problems, important for gerontology:

1) Investigation of the determinants of intrapopulation polymorphism by complex of fitness indices, first of all the life span.

2) Search for effective biomarkers of senescence.

3) Reveal of physiological and genetic mechanisms of action for pharmacological preparations delaying senescence.

4) Investigations of environmental impact on life span, mostly effects of food quality and availability, light and photoperiodic regime, different stressors.

5) Development of models for analysis of certain genetic systems role in manifestation of age-related human diseases

Keywords:

Musca domestica L., house fly, aging, gerontology, fitness, life span

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eISSN: 2221-6197 DOI: 10.31301/2221-6197