eISSN: 2221-6197 DOI: 10.31301/2221-6197

Biomics

Архив номеров

Индексирование
  1. Главная
  2. →
  3. 2017
  4. →
  5. Том 9, № 3
  6. →
  7. Статьи
  8. →
  9. Эволюция методов редактирования геномов

Эволюция методов редактирования геномов

Год: 2017

Страницы: 245-270

Номер: Том 9, №3

Тип: научная статья

Рубрика: Статьи

Авторы: Вершинина Зиля Рифовна, Кулуев Булат Разяпович, Геращенков Григорий Алексеевич, Князев Алексей Викторович, Чемерис Дмитрий Алексеевич, Гумерова (Ясыбаева) Гульнар Рафиловна, Баймиев Алексей Ханифович, Чемерис Алексей Викторович

Скачать pdf

Аннотация:

В статье рассмотрена эволюция методов геномного редактирования, начиная с индуцированного мутагенеза, вызывающего под действием физических факторов или химических агентов случайные мутации в геномах. Индуцированную полиплоидию принято считать геномной мутацией и при этом ее также можно рассматривать как некий вариант редактирования генома в виде полной его дупликации. Отмечено, что для эффективного направленного редактирования геномов любых организмов необходимо внесение двуцепочечных разрывов в целевые места молекул ДНК. Описываются методы направленного мутагенеза с помощью химерных олигонуклеотидов, рекомбинации с использованием мегануклеаз, искусственных молекулярных «ножниц» ARCUT, нуклеаз «цинковых пальцев», нуклеаз на основе эффекторных TAL белков, а также Cas нуклеаз, являющихся составной частью передовой CRISPR/Cas технологии редактирования геномов. Продемонстрирован весомый вклад отечественных ученых в отдельные направления получения мутантных растений, несмотря на чинимые им препятствия. Цитированная литература охватила более чем столетний период.

Ключевые слова:

CRISPR/Cas технология, ZFN технология, TALEN технология, мегануклеазы, химерные олигонуклеотиды, молекулярные «ножницы» ARCUT, мутации, мутагенез, геномное редактирование

Библиографический список:

  1. Баймиев Ан.Х., Кулуев Б.Р., Вершинина З.Р. Князев А.В., Чемерис Д.А., Рожнова Н.А., Геращенков Г.А., Михайлова Е.В., Баймиев Ал.Х., Чемерис А.В. CRISPR/Cas редактирование геномов (растений) и общество // Биомика. 2017. Т.9. С.183-202.
  2. Баутин В.М., Глазко В.И. Сессия ВАСХНИЛ, август 1948 г. Уроки на будущее // Известия ТСХА. 2008. Вып. 3. С.149-175.
  3. Белько Н.Б., Гордей И.С., Гордей И.А., Урбан Э.И. Дупликация генома озимой ржи (Secale cereale L.) с использованием закиси азота (N2O) // Молекулярная и прикладная генетика. 2013. Т.15. С. 64-74.
  4. Гаршин М.В., Картуха А.И., Кулуев Б.Р. «Кок-сагыз: особенности культивирования, перспективы возделывания и внедрения в современное производство» // Биомика. 2016. Том 8. С. 323-333.
  5. Зубов В.В. Секвенирование по Ротбергу (потенциал полупроводникового секвенирования) // Биомика. 2013. Т.5. С.48-61.
  6. Карпеченко Г.Д. Тетраплоидные шестирядные ячменя, полученные обработкой колхицином // Докл. АН СССР. 1940. Т. 27. С. 48-51.
  7. Кулуев Б.Р., Гарафутдинов Р.Р., Максимов И.В., Сагитов А.М., Чемерис Д.А., Князев А.В., Вершинина З.Р., Баймиев Ан.Х., Мулдашев А.А., Баймиев Ал.Х., Чемерис А.В. «Натуральный каучук, его источники и составные части» // Биомика. 2015. Т.7. С. 224-283.
  8. Кулуев Б.Р., Вершинина З.Р., Князев А.В., Чемерис Д.А., Баймиев Ан.Х., Чумаков М.И., Баймиев Ал.Х., Чемерис А.В. ««Косматые» корни растений – важный инструментарий для исследователей и мощная фитохимбиофабрика для производственников» // Биомика. 2015а. Т.7. С.70-120.
  9. Кулуев Б.Р., Бережнева З.А., Чемерис А.В. «Гидропонное и аэропонное выращивание одуванчика Taraxacum kok-saghyz Rodin» // Биомика. 2017. Т.9. С. 96–100.
  10. Кулуев Б.Р., Геращенков Г.А., Рожнова Н.А., Баймиев Ан.Х., Вершинина З.Р., Князев А.В., Матниязов Р.Т., Гумерова Г.Р., Михайлова Е.В., Никоноров Ю.М., Чемерис Д.А., Баймиев Ал.Х., Чемерис А.В. CRISPR/Cas редактирование геномов растений // Биомика. 2017а. Т.9. С.155-182.
  11. Курсанова Т.А. Основоположник отечественной микробиологии. К 150-летию со дня рождения академика Г.А. Надсона // Вестник Российской академии наук. 2017. Т.87. С.663-669.
  12. Миронин С.С. Лысенко был прав! / http://biblioteka-dzvon.narod.ru/docs/Mironin_About_Lysenko.pdf
  13. Митрофанов В.Г. (ред.) Иосиф Абрамович Рапопорт - ученый, воин, гражданин. Очерки, воспоминания, материалы. М.: Наука. 2001. 305 С.
  14. Навашин М.С., Герасимова Е.Н. Введение колхицина через корни с целью получения полиплоидных растений // ДАН СССР. 1940. Т.26. С.689-692.
  15. Навашин М.С., Герасимова Е.Н. Получение тетраплоидного кок-сагыза и его практическое значение // ДАН СССР. 1941. Т.31. С.47-50.
  16. Навашин М.С., Герасимова Е.Н., Чередниченко А.Ф. Тетраплоидный кок-сагыз как повышенно-продуктивный сорт // ДАН СССР. 1945. Т.47. С.450-453.
  17. Навашин М.С., Герасимова-Навашина Е.Н. О тетраплоидии и тетраплоидном кок-сагызе // Агробиология. 1951. №6. С.102-109.
  18. Навашин С. О диморфизме ядер в соматических клетках у Galtonia candicans // Изв. Имп. Акад. Наук. Сер. VI. - 1912. - №4. - С.373-385.
  19. Навашин С. Гетеро- и идиохромозомы растительного ядра, как причина ядерного диморфизма некоторых видов растений, и значение ядерного диморфизма в процессе видообразования // Изв. Имп. Акад. Наук. Сер. VI. 1915. №17. С.1821-1834.
  20. Надсон Г.А. О действии радия на дрожжевые грибки в связи с общей проблемой влияния радия на живое вещество // Вестник рентгенологии и радиологии. 1920. № 1–2. С. 45–137. (цит. по Курсанова Т.А. Основоположник отечественной микробиологии. К 150-летию со дня рождения академика Г.А. Надсона // Вестник Российской академии наук. 2017. Т.87. С.663-669.)
  21. Надсон Г.А., Филиппов Г.С. О влиянии рентгеновых лучей на половой процесс и образование мутантов у низших грибов (Mucoraceae) // Вестник рентгенологии и радиологии. 1925. № 6. С. 305–310. (цит. по Курсанова Т.А. Основоположник отечественной микробиологии. К 150-летию со дня рождения академика Г.А. Надсона // Вестник Российской академии наук. 2017. Т.87. С.663-669.)
  22. Немудрый А.А., Валетдинова К.Р., Медведев С.П., Закиян С.М. Системы редактирования геномов TALEN и CRISPR/Cas – инструменты открытий // Acta Naturae. 2014. Т. 6. С. 20–42.
  23. О положении в биологической науке. Стенографический отчет сессии Всесоюзной академии сельскохозяйственных наук имени В.И.Ленина. 31 июля - 7 августа 1948 г. М.: ОГИЗ – СЕЛЬХОЗГИЗ. Государственное издательство сельскохозяйственной литературы. 1948. 536 С.
  24. Рапопорт И.А. Карбонильные соединения и химический механизм мутаций // Докл. АН СССР. 1946. Т.54. С.65-68.
  25. Рапопорт И.А., Зоз Н.Н., Макарова С.И., Сальникова Т.В. (ред.) Супермутагены / М.: Наука. 1966. 272 С.
  26. Строева О.Г. Иосиф Абрамович Рапопорт 1912-1990. М.: Наука. 2009. 213 С.
  27. Ребриков Д.В., Коростин Д.О., Шубина Е.С., Ильинский В.В. NGS: высокопроизводительное секвенирование / М.: БИНОМ. Лаборатория знаний. 2014. 232 С.
  28. Чемерис Д.А., Кирьянова О.Ю., Геращенков Г.А., Кулуев Б.Р., Рожнова Н.А., Матниязов Р.Т., Баймиев Ан.Х., Баймиев Ал.Х., Губайдуллин И.М., Чемерис А.В. Биоинформатические ресурсы для CRISPR/Cas редактирования геномов // Биомика. 2017. Т.9. С.203-228.
  29. Чугунова А.А., Донцова О.А., Сергиев П.В. Методы изменения геномов: новая эра в молекулярной биологии // Биохимия. 2016. Т. 81. С. 881 898.
  30. Эйгес Н.С. Историческая роль Иосифа Абрамовича Рапопорта в генетике. Продолжение исследований с использованием метода химического мутагенеза // Вавиловский журнал генетики и селекции. 2013. Т. 17. С. 162-172.
  31. Aiba Y., Mori M., Yamamoto Y., Komiyama M. Rapid site-selective hydrolysis of double-stranded DNA by use of Ce (IV)/EDTA and PNA bearing phosphate group // Nucleic Acids Symposium Series. 2005. V. 49. P. 277-278.
  32. Aiba Y., Yamamoto Y., Komiyama M. Highly active artificial restriction enzyme composed of Ce (IV)/EDTA and PNA bearing phosphate group-Relationship between the promotion by phosphate and the structure of invasion complex //Nucleic Acids Symposium Series. 2006. V. 50. P. 255-256.
  33. Alexeev V., Igoucheva O., Domashenko A., Cotsarelis G., Yoon K. Localized in vivo genotypic and phenotypic correction of the albino mutation in skin by RNA-DNA oligonucleotide // Nature biotechnology. 2000. V. 18. P. 43-48.
  34. Alexeev V., Yoon K. Stable and inheritable changes in genotype and phenotype of albino melanocytes induced by an RNA-DNA oligonucleotide // Nature biotechnology. 1998. V. 16. P. 1343-1346.
  35. Aouida M., Eid A., Ali Z., Cradick T., Lee C., Deshmukh H., Atef A., AbuSamra D., Gadhoum S.Z., Merzaban J., Bao G., Mahfouz M. Efficient fdCas9 synthetic endonuclease with improved specificity for precise genome engineering // PLoS One. 2015. V. 10 (7). e0133373.
  36. Arishima H., Yokoyama M., Komiyama M. Site-selective DNA hydrolysis by the combination of Ce (IV) and oligonucleotide bearing EDTA groups // Nucleic Acids Symposium Series. 2003. V. 3. P. 137-138.
  37. Arnould S., Delenda C., Grizot S., Desseaux C., Paques F., Silva G.H., Smith J. The I-CreI meganuclease and its engineered derivatives: applications from cell modification to gene therapy // Protein Engineering, Design and Selection. 2010. V.24. P. 27-31.
  38. Auerbach C., Robson J.M. Production of mutations by allyl isothiocyanate // Nature. 1944. V.154. P.81
  39. Auerbach C., Robson J.M. Chemical production of mutations // Nature. 1946. V.157. P.302.
  40. Bates G.H. Polyploidy induced by colchicine and its economic possibilities // Nature. 1939. V. 144. P.315–316.
  41. Beetham P.R., Kipp P.B., Sawycky X.L., Arntzen C.J., May G.D. A tool for functional plant genomics: chimeric RNA/DNA oligonucleotides cause in vivo gene-specific mutations // Proceedings of the National Academy of Sciences. 1999. V. 96. P. 8774-8778.
  42. Belyaev I., Dean A., Eger H., Hubmann G., Jandrisovits R., Kern M., Kundi M., Moshammer H., Lercher P., Müller K., Oberfeld G., Ohnsorge P., Pelzmann P., Scheingraber C., Thill R. EUROPAEM EMF Guideline 2016 for the prevention, diagnosis and treatment of EMF-related health problems and illnesses // Rev. Environ. Health. 2016. V.31. P.363-397.
  43. Berg J.M. Proposed structure for the zinc-binding domains from transcription factor IIIA and related proteins // Proc. Natl. Acad. Sci. USA. 1988. V.85. P.99–102.
  44. Bibikova M., Beumer K., Trautman J.K., Carroll D. Enhancing gene targeting with designed zinc finger nucleases // Science. 2003. V. 300. P. 764-764.
  45. Blakeslee A.F., Avery A.G. Methods of inducing doubling of chromosomes in plants: by treatment with colchicine // Journal of Heredity. 1937. V.28. P.393–411.
  46. Bitinaite J., Wah D.A., Aggarwal A.K., Schildkraut I. FokI dimerization is required for DNA cleavage // Proc. Natl. Acad. Sci. USA. 1998. V.95. P.10570-10575.
  47. Boch J., Scholze H., Schornack S., Landgraf A., Hahn S., Kay S., .Lahaye T., Nickstadt A., Bonas, U. Breaking the code of DNA binding specificity of TAL-type III effectors // Science. 2009. V. 326. P. 1509-1512.
  48. Bogdanove A.J., Booher N.J. Online Tools for TALEN Design // TALENs: Methods and Protocols. 2016. P. 43-47.
  49. Bonas U., Stall R.E., Staskawicz B. Genetic and structural characterization of the avirulence gene avrBs3 from Xanthomonas campestris pv. vesicatoria // Molecular and General Genetics MGG. 1989. V. 218. P. 127-136.
  50. Bonde M.T., Klausen M.S., Anderson M.V., Wallin A.I., Wang H.H., Sommer M.O. MODEST: a web-based design tool for oligonucleotide-mediated genome engineering and recombineering // Nucleic Acids Research. 2014. V. 42 (W1). W408-W415.
  51. Booher N.J., Bogdanove A.J. Tools for TAL effector design and target prediction // Methods. 2014. V. 69. P. 121-127.
  52. Bose J.L. Chemical and UV Mutagenesis // The Genetic Manipulation of Staphylococci: Methods and Protocols. 2016. P. 111-115.
  53. Breyer D., Herman P., Brandenburger A., Gheysen G., Remaut E., Soumillion P., Van Doorsselaere J., Custers R., Pauwels K., Sneyers M., Reheul D. Commentary: Genetic modification through oligonucleotide-mediated mutagenesis. A GMO regulatory challenge? // Environmental Biosafety Research. 2009. V. 8. P. 57-64.
  54. Cai C.Q., Doyon Y., Ainley W.M., Miller J.C., DeKelver R.C., Moehle E.A., Rock J.M., Lee Y.L., Garrison R., Schulenberg L., Blue R., Worden A., Baker L., Faraji F., Zhang L., Holmes M.C., Rebar E.J., Collingwood T.N., Rubin-Wilson B., Gregory P.D., Urnov F.D., Petolino J.F. Targeted transgene integration in plant cells using designed zinc finger nucleases // Plant Molecular Biology. 2009. V. 69. P. 699-709.
  55. Cermak T., Doyle E.L., Christian M., Wang L., Zhang Y., Schmidt C., Baller J.A., Somia N.V., Bogdanove A.J., Voytas D.F. Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting // Nucleic Acids Research. 2011. V. 39. e82.
  56. Char S.N., Unger‐Wallace E., Frame B., Briggs S.A., Main M., Spalding M. H., Vollbrecht E., Wang K., Yang B. Heritable site‐specific mutagenesis using TALENs in maize // Plant Biotechnology Journal. 2015. V. 13. P. 1002-1010.
  57. Chen F., Pruett-Miller S.M., Huang Y., Gjoka M., Duda K., Taunton J., Collingwood T.N., Frodin M., Davis G.D. High-frequency genome editing using ssDNA oligonucleotides with zinc-finger nucleases // Nature Methods. 2011. V. 8. P. 753-755.
  58. Chen K., Gao C. TALENs: customizable molecular DNA scissors for genome engineering of plants // Journal of Genetics and Genomics. 2013. V.40. P. 271-279.
  59. Chen W., Kitamura Y., Zhou J.M., Sumaoka J., Komiyama M. Site-selective DNA hydrolysis by combining Ce (IV)/EDTA with monophosphate-bearing oligonucleotides and enzymatic ligation of the scission fragments // Journal of the American Chemical Society. 2004. V. 126. P. 10285-10291.
  60. Christian M., Qi Y., Zhang Y., Voytas D.F. Targeted mutagenesis of Arabidopsis thaliana using engineered TAL effector nucleases // G3: Genes, Genomes, Genetics. 2013. V. 3. P. 1697-1705.
  61. Clasen B.M., Stoddard T.J., Luo S., Demorest Z.L., Li J., Cedrone F., Tibebu R., Davison S., Ray E.E., Daulhac A., Coffman A. Yabandith A., Retterath A., Haun W., Baltes N.J., Mathis L., Voytas D.F., Zhang F. Improving cold storage and processing traits in potato through targeted gene knockout // Plant biotechnology journal. 2016. V. 14. P. 169-176.
  62. Cole-Strauss A., Yoon K., Xiang Y., Byrne B.C., Rice M.C., Gryn J., Holloman W.K., Kmiec E.B. Correction of the mutation responsible for sickle cell anemia by an RNA-DNA oligonucleotide // Science. 1996. V. 273. P. 1386-1388.
  63. Coontz R. Science's top 10 breakthroughs of 2013. (http://www.sciencemag.org/news/2013/12/sciences-top-10-breakthroughs-2013).
  64. Cradick T.J., Ambrosini G., Iseli C., Bucher P., McCaffrey A.P. ZFN-site searches genomes for zinc finger nuclease target sites and off-target sites // BMC Bioinformatics. 2011. V.12:152.
  65. Curtin S.J., Zhang F., Sander J.D., Haun W.J., Starker C., Baltes N.J., Reyon D., Dahlborg E.J., Goodwin M.J., Coffman A.P., Dobbs D., Joung J.K., Voytas D.F., Stupar R.M. Targeted mutagenesis of duplicated genes in soybean with zinc-finger nucleases // Plant physiology. 2011. V. 156. P. 466-473.
  66. Dhaliwal A.K., Mohan A., Sidhu G., Maqbool R., Gill K.S. An ethylmethane sulfonate mutant resource in pre-Green revolution hexaploid wheat // PLoS One. 2015. V.10(12):e0145227.
  67. D’Halluin K., Vanderstraeten C., Stals E., Cornelissen M., Ruiter R. Homologous recombination: a basis for targeted genome optimization in crop species such as maize // Plant Biotechnology J. 2008. V. 6. P. 93-102.
  68. D'Halluin K., Vanderstraeten C., Hulle J., Rosolowska J., Den Brande I., Pennewaert A., D'Hont K., Bossut M., Jantz D., Ruiter R., Broadhvest J. Targeted molecular trait stacking in cotton through targeted double‐strand break induction // Plant Biotechnology J. 2013. V. 11. P. 933-941.
  69. De Pater S., Neuteboom L.W., Pinas J.E., Hooykaas P.J., Van Der Zaal B.J. ZFN‐induced mutagenesis and gene‐targeting in Arabidopsis through Agrobacterium‐mediated floral dip transformation // Plant Biotechnology Journal. 2009. V. 7. P. 821-835.
  70. Dong C., Beetham P., Vincent K., Sharp P. Oligonucleotide-directed gene repair in wheat using a transient plasmid gene repair assay system // Plant Cell Reports. 2006. V. 25. P. 457-465.
  71. Doyle E.L., Booher N.J., Standage D.S., Voytas D.F., Brendel V.P., Vandyk J.K., Bogdanove A.J. TAL Effector-Nucleotide Targeter (TALE-NT) 2.0: tools for TAL effector design and target prediction // Nucleic Acids Res. 2012. V.40. (Web Server issue). W117-122.
  72. Dreier B., Beerli R.R., Segal D.J., Flippin J.D., Barbas C.F. 3rd. Development of zinc finger domains for recognition of the 5'-ANN-3' family of DNA sequences and their use in the construction of artificial transcription factors // J. Biol. Chem. 2001. V.276. P.29466-29478.
  73. Dreier B., Fuller R.P., Segal D.J., Lund C.V., Blancafort P., Huber A., Koksch B., Barbas C.F. 3rd. Development of zinc finger domains for recognition of the 5'-CNN-3' family DNA sequences and their use in the construction of artificial transcription factors // J. Biol. Chem. 2005. V.280. P.35588-35597.
  74. Du Y., Li W., Yu L., Chen G., Liu Q., Luo S., Shu Q., Zhou L. Mutagenic effects of carbon-ion irradiation on dry Arabidopsis thaliana seeds // Mutation Research / Genetic Toxicology and Environmental Mutagenesis. 2014. V. 759. P. 28-36.
  75. Durai S., Mani M., Kandavelou K., Wu J., Porteus M. H., Chandrasegaran S. Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cells // Nucleic acids research. 2005. V. 33. P. 5978-5990.
  76. Eigsti O.J. A cytological study of colchicine effects in the induction of polyploidy in plants // Proc. Natl. Acad. Sci. USA. 1938. V.24. P.56-63.
  77. Eigsti O.J., Dustin P., Jr. / Colchicine in Agriculture, Medicine, Biology and Chemistry. The Iowa State College Press, Ames, lowa, U.S.A. 1955. 470 P.
  78. Elmas O. Effects of electromagnetic field exposure on the heart: a systematic review // Toxicol. Ind. Health. 2016. V.32. P.76-82.
  79. Epinat J.C., Arnould S., Chames P., Rochaix P., Desfontaines D., Puzin C., Patin A., Zanghellini A., Paques F., Lacroix E. A novel engineered meganuclease induces homologous recombination in yeast and mammalian cells // Nucleic Acids Research. 2003. V. 31. P. 2952-2962.
  80. Fine E.J., Cradick T.J., Zhao C.L., Lin Y., Bao G. An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage // Nucleic Acids Res. 2014. V.42(6):e42.
  81. François J.C., Saison-Behmoaras T., Chassignol M., Thuong N.T., Sun J.S., Hélène C. Periodic cleavage of poly(dA) by oligothymidylates covalently linked to the 1,10-phenanthroline-copper complex // Biochemistry. 1988. V.27. P.2272-2276.
  82. Fu F., Sander J.D., Maeder M., Thibodeau-Beganny S., Joung J.K., Dobbs D., Miller L., Voytas D.F. Zinc Finger Database (ZiFDB): a repository for information on C2H2 zinc fingers and engineered zinc-finger arrays // Nucleic Acids Res. 2009. (Database issue):D279-83.
  83. Fujii W., Kano K., Sugiura K., Naito K. Repeatable construction method for engineered zinc finger nuclease based on overlap extension PCR and TA-cloning // PloS one. 2013. V. 8 (3). e59801.
  84. Gaj T., Gersbach C.A., Barbas C.F. ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering // Trends in Biotechnology. 2013. V. 31. P. 397-405.
  85. Galindo-Gonzalez L., Pinzon-Latorre D., Bergen E.A., Jensen D.C., Deyholos M.K. Ion Torrent sequencing as a tool for mutation discovery in the flax (Linum usitatissimum L.) genome // Plant Methods. 2015. V. 11 (19).
  86. Grau J., Boch J., Posch S. TALENoffer: genome-wide TALEN off-target prediction // Bioinformatics. 2013. V.29. P.2931-2932.
  87. Grau J., Wolf A., Reschke M., Bonas U., Posch S., Boch J. Computational predictions provide insights into the biology of TAL effector target sites. PLOS Computational Biology. 2013a. 9(3): e1002962.
  88. Grau J., Reschke M., Erkes A., Streubel J., Morgan R.D., Wilson G.G., Koebnik R., Boch J. AnnoTALE: bioinformatics tools for identification, annotation, and nomenclature of TALEs from Xanthomonas genomic sequences // Sci. Rep. 2016. V.6:21077.
  89. Guilinger J.P., Thompson D.B., Liu D.R. Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification // Nat. Biotechnol. 2014. V. 32. P. 577–582.
  90. Halgamuge M.N. Review: Weak radiofrequency radiation exposure from mobile phone radiation on plants // Electromagn. Biol. Med. 2017. V.36. P.213-235.
  91. Havlicek S., Shen Y., Alpagu Y., Bruntraeger M.B., Zufir N.B., Phuah Z.Y., Fu Z., Dunn N.R., Stanton L.W. Re-engineered RNA-guided FokI-nucleases for improved genome editing in human cells // Mol. Ther. 2017. V.25. P.342-355.
  92. Hase Y., Shimono K., Inoue M., Tanaka A., Watanabe H. Biological effects of ion beams in Nicotiana tabacum L // Radiation and Environmental Biophysics. 1999. V. 38. P. 111-115.
  93. Haun W., Coffman A., Clasen B.M., Demorest Z.L., Lowy A., Ray E., Retteran A., Stoddard T., Juillerat A., Cedrone F., Mathis, L., Voytas D.F., Zhang F. Improved soybean oil quality by targeted mutagenesis of the fatty acid desaturase 2 gene family // Plant Biotechnology Journal. 2014. V. 12. P. 934-940.
  94. Heigwer F., Kerr G., Walther N., Glaeser K., Pelz O., Breinig M., Boutros M. E-TALEN: a web tool to design TALENs for genome engineering // Nucleic Acids Res. 2013. V.41(20):e190.
  95. Hendel A., Fine E.J., Bao G., Porteus M.H. Quantifying on-and off-target genome editing // Trends in Biotechnology. 2015. V. 33. P. 132-140.
  96. Hilioti Z., Ganopoulos I., Ajith S., Bossis I., Tsaftaris A. A novel arrangement of zinc finger nuclease system for in vivo targeted genome engineering: the tomato LEC1-LIKE4 gene case // Plant Cell Reports. 2016. V. 35. P. 2241-2255.
  97. Hurt J.A., Thibodeau S.A., Hirsh A.S., Pabo C.O., Joung J.K. Highly specific zinc finger proteins obtained by directed domain shuffling and cell-based selection // Proceedings of the National Academy of Sciences. 2003. V. 100. P. 12271-12276.
  98. Ito K., Katada H., Shigi N., Komiyama M. Site-selective scission of human genome by artificial restriction DNA cutter // Chemical Communications. 2009. N. 43. P. 6542-6544.
  99. Jamieson A.C., Miller J.C., Pabo C.O. Drug discovery with engineered zinc-finger proteins // Nature Rev. Drug Discov. 2003. V.2. P.361–368.
  100. Jasin M., Haber J.E. The democratization of gene editing: Insights from site-specific cleavage and double-strand break repair // DNA repair. 2016. V. 44. С. 6-16.
  101. Javadian N., Karimzadeh G., Sharifi M., Moieni A., Behmanesh M. In vitro polyploidy induction: changes in morphology, podophyllotoxin biosynthesis, and expression of the related genes in Linum album (Linaceae) // Planta. 2017. V.245. P.1165-1178.
  102. Jayakanthan M., Muthukumaran J., Chandrasekar S., Chawla K., Punetha A., Sundar D. ZifBASE: a database of zinc finger proteins and associated resources // BMC Genomics. 2009. V. 10 (421).
  103. Jung J.H., Altpeter F. TALEN mediated targeted mutagenesis of the caffeic acid O-methyltransferase in highly polyploid sugarcane improves cell wall composition for production of bioethanol // Plant Molecular Biology. 2016. V. 92. P. 131-142.
  104. Kamburova V.S., Nikitina E.V., Shermatov S.E., Buriev Z.T., Kumpatla S.P., Emani C., Abdurakhmonov I.Y. Genome Editing in Plants: An Overview of Tools and Applications // International Journal of Agronomy. 2017. V. 2017.
  105. Katada H., Chen H.J., Shigi N., Komiyama M. Homologous recombination in human cells using artificial restriction DNA cutter // Chemical Communications. 2009. N. 43. P. 6545-6547.
  106. Katada H., Komiyama M. Artificial restriction DNA cutters as new tools for gene manipulation // ChemBioChem. 2009. V. 10. P. 1279-1288.
  107. Katada H., Komiyama M. Artificial restriction DNA cutters to promote homologous recombination in human cells // Current Gene Therapy. 2011. V. 11. P. 38-45.
  108. Kay S., Hahn S., Marois E., Hause G., Bonas U. A bacterial effector acts as a plant transcription factor and induces a cell size regulator // Science. 2007. V. 318. P. 648-651.
  109. Kim S., Kim J.S. Targeted genome engineering via zinc finger nucleases // Plant Biotechnology Reports. 2011. V. 5. P. 9-17.
  110. Kim Y., Kweon J., Kim J.S. TALENs and ZFNs are associated with different mutation signatures // Nature Methods. 2013. V. 10. P. 185-185.
  111. Kim Y.G., Cha J., Chandrasegaran S. Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain // Proc. Natl. Acad. Sci. USA. 1996. V.93. P.1156-1160.
  112. Kmiec E.B., Cole A., Holloman W.K. The REC2 gene encodes the homologous pairing protein of Ustilago maydis // Molecular and Cellular Biology. 1994. V. 14. P. 7163-7172.
  113. Kochevenko A., Willmitzer L. Chimeric RNA/DNA oligonucleotide-based site-specific modification of the tobacco acetolactate syntase gene // Plant Physiology. 2003. V. 132. P. 174-184.
  114. Kodym A., Afza R. Physical and chemical mutagenesis // Methods Mol. Biol. 2003. V.236. P.189-204.
  115. Komiyama M., Takeda N., Shiiba T., Takahashi Y., Matsumoto Y., Yashiro M. Rare earth metal ions for DNA hydrolyses and their use to artificial nuclease // Nucleosides and Nucleotides. 1994. V.13. P.1297-1309.
  116. Komiyama M. Chemical modifications of artificial restriction DNA cutter (ARCUT) to promote its in vivo and in vitro applications. // Artif. DNA, PNA, XNA. 2014. V.5(3):e1112457.
  117. Kumar S., Allen G.C., Thompson W.F. Gene targeting in plants: fingers on the move // Trends in Plant Science. 2006. V. 11. P. 159-161.
  118. Kusano H., Onodera H., Kihira M., Aoki H., Matsuzaki H., Shimada H. A simple Gateway-assisted construction system of TALEN genes for plant genome editing // Scientific Reports. 2016. V. 6 (30234).
  119. Labun K., Montague T.G., Gagnon J.A., Thyme S.B., Valen E. CHOPCHOP v2: a web tool for the next generation of CRISPR genome engineering // Nucleic Acids Res. 2016. V. 44. P. W272-W276.
  120. Li F., Wang T., Xu S., Yuan H., Bian P., Wu Y., Wu L., Yu Z. Abscopal mutagenic effect of low-energy-ions in Arabidopsis thaliana seeds // International Journal of Radiation Biology. 2011. V. 87. P. 984-992.
  121. Li T., Liu B., Spalding M.H., Weeks D.P., Yang B. High-efficiency TALEN-based gene editing produces disease-resistant rice // Nature biotechnology. 2012. V. 30 (5). P. 390-392.
  122. Li L., Wu L.P., Chandrasegaran S. Functional domains in Fok I restriction endonuclease // Proc. Natl. Acad. Sci. USA. 1992. V.89. P.4275-4279.
  123. Li Z., Jiang L., Ma Y., Wei Z., Hong H., Liu Z., Lei J., Liu Y., Guan R., Guo Y., Jin L., Zhang L., Li Y., Ren Y., He W., Liu M., Htwe N.M., Liu L., Guo B., Song J., Tan B., Liu G., Li M., Zhang X., Liu B., Shi X., Han S., Hua S., Zhou F., Yu L., Li Y., Wang S., Wang J., Chang R., Qiu L. Development and utilization of a new chemically-induced soybean library with a high mutation density // J. Integr. Plant Biol. 2017. V.59. P.60-74.
  124. Lin Y., Fine E.J., Zheng Z., Antico C.J., Voit R.A., Porteus M.H., Cradick T.J., Bao G. SAPTA: a new design tool for improving TALE nuclease activity // Nucleic Acids Res. 2014. V.42(6):e47.
  125. Ling A.P.K., Ung Y.C., Hussein S., Harun A.R., Tanaka A., Yoshihiro H. Morphological and biochemical responses of Oryza sativa L.(cultivar MR219) to ion beam irradiation // Journal of Zhejiang University. 2013. V. 14. P. 1132-1143.
  126. Liu Q., Segal D.J., Ghiara J.B., Barbas C.F. Design of polydactyl zinc-finger proteins for unique addressing within complex genomes // Proceedings of the National Academy of Sciences. 1997. V. 94. P. 5525-5530.
  127. Liu Q., Xia Z.Q., Case C.C. Validated zinc finger protein designs for all 16 GNN DNA triplet targets // Journal of Biological Chemistry. 2002. V.277. P. 3850-3856.
  128. Lloyd A., Plaisier C.L., Carroll D., Drews G.N. Targeted mutagenesis using zinc-finger nucleases in Arabidopsis // Proceedings of the National Academy of Sciences of the United States of America. 2005. V. 102. P. 2232-2237.
  129. Maeder M.L., Thibodeau-Beganny S., Osiak A., Wright D.A., Anthony R.M., Eichtinger M., Jiang T., Foley J.E., Winfrey R.J., Townsend J.A., Unger-Wallace E., Sander J.D., Müller-Lerch F., Fu F., Pearlberg J., Göbel C., Dassie J.P., Pruett-Miller S.M., Porteus M.H., Sgroi D.C., Iafrate A.J., Dobbs D., McCray P.B.Jr., Cathomen T., Voytas D.F., Joung J.K. Rapid “open-source” engineering of customized zinc-finger nucleases for highly efficient gene modification // Molecular Cell. 2008. V. 31. P. 294-301.
  130. Maeder M.L., Thibodeau-Beganny S., Sander J.D., Voytas D.F., Joung J.K. Oligomerized Pool ENgineering (OPEN): An “Open-Source” Protocol for Making Customized Zinc Finger Arrays // Nature Protocols. 2009. V. 4. P. 1471-1501.
  131. Mak A.N.S., Bradley P., Bogdanove A.J., Stoddard B.L. TAL effectors: function, structure, engineering and applications // Current Opinion in Structural Biology. 2013. V. 23. P. 93-99.
  132. Malzahn A., Lowder L., Qi Y. Plant genome editing with TALEN and CRISPR // Cell and Bioscience. 2017. V. 7 (21).
  133. Mandell J.G.; Barbas C.F., III. Zinc finger tools: custom DNA-binding domains for transcription factors and nucleases // Nucleic Acids Research. 2006. V. 34. W516-W523.
  134. Mani M., Smith J., Kandavelou K., Berg J.M., Chandrasegaran S. Binding of two zinc finger nuclease monomers to two specific sites is required for effective double-strand DNA cleavage // Biochemical and Biophysical Research Communications. 2005. V. 334. P. 1191-1197.
  135. Marton I., Zuker A., Shklarman E., Zeevi V., Tovkach A., Roffe S., Ovadis M., Tzfira T., Vainstein A. Nontransgenic genome modification in plant cells // Plant Physiology. 2010. V. 154. P. 1079-1087.
  136. Matsumoto Y., Komiyama M. DNA hydrolysis by rare-earth metal ions // Nucleic Acids Symp. Ser. 1992. V.27. P.33-34.
  137. Miller J.C., Tan S., Qiao G., Barlow K.A., Wang J., Xia D.F., Meng X., Paschon D.E., Leung E., Hinkley S.J., Dulay G P., Hua K.L., Ankoudinova I., Cost G.J., Urnov F.D., Zhang H.S., Holmes M.C., Zhang L., Gregory P.D., Rebar E.J. A TALE nuclease architecture for efficient genome editing // Nature Biotechnology. 2011. V. 29. P. 143-148.
  138. Mondal S., Petwal V.C., Badigannavar A.M., Bhad P.G., Verma V.P., Goswami S.G., Dwivedi J. Electron beam irradiation revealed genetic differences in radio-sensitivity and generated mutants in groundnut (Arachis hypogaea L.) // Applied Radiation and Isotopes. 2017. V. 122. P. 78-83.
  139. Montague T.G., Cruz J.M., Gagnon J.A., Church G.M., Valen E. CHOPCHOP: a CRISPR/Cas9 and TALEN web tool for genome editing // Nucleic Acids Res. 2014. V. 42. P. W401–407.
  140. Morbitzer R., Römer P., Boch J., Lahaye T. Regulation of selected genome loci using de novo-engineered transcription activator-like effector (TALE)-type transcription factors // Proc. Natl. Acad. Sci. USA. 2010. V.107. P.21617-21622.
  141. Moscou M. J., Bogdanove A. J. A simple cipher governs DNA recognition by TAL effectors // Science. 2009. V. 326. P. 1501-1501.
  142. Moser H.E., Dervan P.B. Sequence-specific cleavage of double helical DNA by triple helix formation // Science. 1987. V.238. P.645-650.
  143. Muller H.J. Artificial transmutation of the gene // Science. 1928. V.66. P.84-87.
  144. Mussolino C., Cathomen T. TALE nucleases: tailored genome engineering made easy //Current Opinion in Biotechnology. 2012. V. 23. P. 644-650.
  145. Muthusamy A., Jayabalan N. Variations in seed protein content of cotton (Gossypium hirsutum L.) mutant lines by in vivo and in vitro mutagenesis // J. Environ. Biol. 2013. V.34. P.11-16.
  146. Nadson G. Influence des rayons X sur la sexualite et la formation des mutantes chez les Champignons inferieurs (Mucorinees) // Compt. Rend. Soc. Biol. 1925. V. 98. P. 473–475. (цит. по Курсанова Т.А. Основоположник отечественной микробиологии. К 150-летию со дня рождения академика Г.А. Надсона // Вестник Российской академии наук. 2017. Т.87. С.663-669.)
  147. Navashin M. «Amphiplastie» - eine neue Karyologische Erscheinung // Ztschr. ind. Abst. und Verebungslehre. - 1928. - V.2. - Suppl. - S.1148-1152. (русский перевод — М.С. Навашин «Амфипластия» - новое кариологическое явление // В кн.: Проблемы кариологии и цитогенетики в исследованиях на видах рода Crepis. - М.: Наука. 1985. С.108-111.)
  148. Nawaschin S. Resultate einer Revision der Befruchtungsvorgange bei Lilium Martagon und Fritillaria tenella // Изв. Имп. Акад. Наук. 1898. Т.9. С.377-382.
  149. Neff K.L., Argue D.P., Ma A.C., Lee H.B., Clark K.J., Ekker S.C. Mojo Hand, a TALEN design tool for genome editing applications // BMC Bioinformatics. 2013. V.14:1.
  150. Nilan R.A. Increasing the effectiveness, efficiency, and specificity of mutation induction in flowering plants // Genes, Enzymes, and Populations. 1973. P. 205-222.
  151. Okuzaki A., Toriyama K. Chimeric RNA/DNA oligonucleotide-directed gene targeting in rice // Plant Cell Reports. 2004. V. 22. P. 509-512.
  152. Osakabe Y., Osakabe K. Genome editing with engineered nucleases in plants // Plant and Cell Physiology. 2014. V. 56. P. 389-400.
  153. Pacher M., Puchta H. From classical mutagenesis to nuclease‐based breeding–directing natural DNA repair for a natural end‐product // The Plant Journal. 2017. V. 90. P. 819-833.
  154. Paszkowski J., Baur M., Bogucki A., Potrykus I. Gene targeting in plants // EMBO J. 1988. V. 20. P. 4021–4026.
  155. Pauwels K., Podevin N., Breyer D., Carroll D., Herman P. Engineering nucleases for gene targeting: safety and regulatory considerations // New Biotechnology. 2014. V. 31. P. 18-27.
  156. Pavletich N.P., Pabo C.O. Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A // Science. 1991. V.252. P.809-817.
  157. Peer R., Rivlin G., Golobovitch S., Lapidot M., Gal-On A., Vainstein A., Tzfira T., Flaishman M.A. Targeted mutagenesis using zinc-finger nucleases in perennial fruit trees // Planta. 2015. V. 241. P. 941-951.
  158. Pérez-Quintero A.L., Rodriguez-R L.M., Dereeper A., López C., Koebnik R., Szurek B., Cunnac S. An improved method for TAL effectors DNA-binding sites prediction reveals functional convergence in TAL repertoires of Xanthomonas oryzae strains // PLoS One. 2013. V.8(7):e68464.
  159. Periwal V. A comprehensive overview of computational resources to aid in precision genome editing with engineered nucleases // Brief Bioinform. 2017. V.18. P.698-711.
  160. Petolino J.F. Genome editing in plants via designed zinc finger nucleases // In Vitro Cellular and Developmental Biology. 2015. V. 51. P. 1-8.
  161. Podhajska A.J., Szybalski W. Conversion of the FokI endonuclease to a universal restriction enzyme: cleavage of phage M13mp7 DNA at predetermined sites // Gene. 1985. V.40. P.175-182.
  162. Puchta H., Dujon B., Hohn B. Homologous recombination in plant cells is enhanced by in vivo induction of double strand breaks into DNA by a site-specific endonuclease // Nucleic Acids Res. 1993. V. 21. P. 5034–5040.
  163. Puchta H., Dujon B., Hohn B. Two different but related mechanisms are used in plants for the repair of genomic double-strand breaks by homologous recombination // Proc. Natl. Acad. Sci. USA. 1996. V. 93. P. 5055–5060.
  164. Ramirez C.L., Foley J.E., Wright D.A., Müller-Lerch F., Rahman S.H., Cornu T.I., .Winfrey R.J., Sander J.D., Fu F., Townsend J.A., Cathomen T., Voytas D.F., Joung J.K. Unexpected failure rates for modular assembly of engineered zinc fingers // Nature Methods. 2008. V. 5 (5). P. 374-375.
  165. Randolph L.F. An evaluation of induced polyploidy as a method of breeding crop plants // The American Naturalist. 1941. V. 75. P. 347-363.
  166. Reyon D., Kirkpatrick J.R., Sander J.D., Zhang F., Voytas D.F., Joung J.K., Dobbs D., Coffman C.R. ZFNGenome: a comprehensive resource for locating zinc finger nuclease target sites in model organisms // BMC Genomics. 2011. V.12:83.
  167. Richter A., Streubel J., Boch J. TAL effector DNA-binding principles and specificity // TALENs: Methods and Protocols. 2016. P. 9-25.
  168. Richter A., Streubel J., Boch J. TAL effector DNA-binding principles and specificity // TALENs: Methods and Protocols. 2016. V.1338. P. 9-25.
  169. Rizwan M., Aslam M., Asghar M.J., Abbas G., Shah T.M., Shimelis H. Pre-breeding of lentil (Lens culinaris Medik.) for herbicide resistance through seed mutagenesis // PLoS One. 2017. V.12(2):e0171846.
  170. Rosen L.E., Morrison H.A., Masri S., Brown M.J., Springstubb B., Sussman D., Stoddard B.L. Seligman L.M. Homing endonuclease I-CreI derivatives with novel DNA target specificities // Nucleic Acids Research. 2006. V. 34. P. 4791-4800.
  171. Rowson J.M. Increased alkaloidal contents of induced polyploids of Datura // Nature. 1944. V.154. P.81-82.
  172. Ruiter R., Van Den Brande I., Stals E., Delaure S., Cornelissen M., D'halluin, K. Spontaneous mutation frequency in plants obscures the effect of chimeraplasty // Plant Molecular Biology. 2003. V. 53. P. 715-729.
  173. Salomon S., Puchta H. Capture of genomic and T‐DNA sequences during double‐strand break repair in somatic plant cells // The EMBO Journal. 1998. V. 17. P. 6086-6095.
  174. Samanta M.K., Dey A., Gayen S. CRISPR/Cas9: an advanced tool for editing plant genomes // Transgenic Research. 2016. V. 25. P. 561-573.
  175. Sander J.D., Zaback P.Z., Joung J.K., Voytas D.F., Dobbs D. Zinc Finger Targeter (ZiFiT): an engineered zinc finger/target site design tool // Nucleic Acids Research. 2007. V.35. W599-605.
  176. Sander J.D., Maeder M.L., Reyon D., Voytas D.F., Joung J.K., Dobbs D. ZiFiT (Zinc Finger Targeter): an updated zinc finger engineering tool // Nucleic Acids Research. 2010. V.38. W462-468.
  177. Sapehin, A. A. Röntgen-Mutationen beim Weizen (Triticum vulgare) // Der Züchter. 1930. V.2. P.257-259.
  178. Sauer N.J., Mozoruk J., Miller R.B., Warburg Z.J., Walker K.A., Beetham P.R., Schopke C.R., Gocal G.F. Oligonucleotide‐directed mutagenesis for precision gene editing // Plant Biotechnology Journal. 2016. V. 14. P. 496-502.
  179. Segal D.J., Dreier B., Beerli R.R., Barbas C.F. 3rd. Toward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5'-GNN-3' DNA target sequences // Proc. Natl. Acad. Sci. USA. 1999. V.96. P.2758-2763.
  180. Segal D.J., Beerli R.R., Blancafort P., Dreier B., Effertz K., Huber A., Koksch B., Lund V., Magnenat L., Valente D., Barbas C.F. Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins // Biochemistry. 2003. V. 42. P. 2137-2148.
  181. Shan Q., Zhang Y., Chen K., Zhang K., Gao C. Creation of fragrant rice by targeted knockout of the OsBADH2 gene using TALEN technology // Plant Biotechnology Journal. 2015. V. 13. P. 791-800.
  182. Shigi N., Sumaoka J., Komiyama M. Applications of PNA-based artificial restriction DNA cutters // Molecules. 2017. V.22. pii: E1586.
  183. Shimamura T. Cytological studies of polyploidy induced by colchicine // Cariologia. 1939. V.9. P.476-494.
  184. Shukla V.K., Doyon Y., Miller J.C., DeKelver R.C., Moehle E.A., Worden S.E., Mitchell J.C., Arnold N.L., Gopalan S., Meng X., Choi V.M., Rock J.M., Wu Y.Y., Katibah G.E., Zhifang G., McCaskill D., Simpson M.A., Blakeslee B., Greenwalt S.A., Butler H.J., Hinkley S.J., Zhang L., Rebar E.J., Gregory P.D., Urnov F.D. Precise genome modification in the crop species Zea mays using zinc-finger nucleases // Nature. 2009. V. 459. P. 437-441.
  185. Smith J., Bibikova M., Whitby F.G., Reddy A.R., Chandrasegaran S., Carroll D. Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains // Nucleic Acids Research. 2000. V. 28. P. 3361-3369.
  186. Smith J., Grizot S., Arnould S., Duclert A., Epinat J.C., Chames P., .Prieto J., Redondo P., Blanco F.J., Bravo J.,. Montoya G., Paques F., Duchateau P. A combinatorial approach to create artificial homing endonucleases cleaving chosen sequences // Nucleic acids research. 2006. V. 34. N. 22. e149.
  187. Song D., Wu G., Vrinten P., Qiu X. Development of imidazolinone herbicide tolerant borage (Borago officinalis L.) // Plant Sci. 2017. V.262. P.74-80.
  188. Soriano-Carot M. Addgene: a global scientific resource // http://www.postdocjournal.com/file_journal/2912_90252780.pdf
  189. Souza P.F., Silva F.D., Carvalho F.E., Silveira J.A., Vasconcelos I.M., Oliveira J.T. Photosynthetic and biochemical mechanisms of an EMS-mutagenized cowpea associated with its resistance to cowpea severe mosaic virus // Plant Cell Rep. 2017. V.36. P.219-234.
  190. Soyfer V.N. New light on the Lysenko era // Nature. 1989. V.339. P.415-420.
  191. Stadler L.J. Genetic effects of X-rays in maize // Proc. Natl. Acad. Sci. USA. 1928. V.14. P.69-75.
  192. Stadler L.J. Chromosome number and the mutation rate in Avena and Triticum // Proc. Natl. Acad. Sci. USA. 1929. V.15. P.876-881.
  193. Stadler L.J. Some genetic effects of X-rays in plants // Journal of Heredity. 1930. V.21. P.3–20.
  194. Steinert J., Schiml S., Puchta H. Homology-based double-strand break-induced genome engineering in plants // Plant Cell Reports. 2016. V. 35. P. 1429-1438.
  195. Sugisaki H., Kanazawa S. New restriction endonucleases from Flavobacterium okeanokoites (FokI) and Micrococcus luteus (MluI) // Gene. 1981. V.16. P.73-78.
  196. Surson S., Sitthaphanit S., Wongma N. In vivo induction of tetraploid in tangerine citrus plants (Citrus reticulata Blanco) with the use of colchicine // Pak. J. Biol. Sci. 2015. V.18. P.37-41.
  197. Thole J.M., Strader L.C. Next-generation sequencing as a tool to quickly identify causative EMS-generated mutations // Plant Signaling and Behavior. 2015. V. 10 (5). e1000167-1.
  198. Tovkach A., Zeevi V., Tzfira T. A toolbox and procedural notes for characterizing novel zinc finger nucleases for genome editing in plant cells // The Plant Journal. 2009. V. 57. P. 747-757.
  199. Townsend J.A., Wright D.A., Winfrey R.J., Fu F., Maeder M.L., Joung J.K., Voytas D.F. High frequency modification of plant genes using engineered zinc finger nucleases //Nature. 2009. V. 459. P. 442-445.
  200. Travis J. Making the cut. CRISPR genome-editing technology shows its power // Science. 2015. V.350. P.1456-1457.
  201. Tsai S.Q., Wyvekens N., Khayter C., Foden J.A., Thapar V., Reyon D., Goodwin M.J., Aryee M.J., Joung J.K. Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing // Nat. Biotechnol. 2014. V.32. P.569-576.
  202. Tulay E., Unal M. Production of colchicine induced tetraploids in Vicia villosa roth // Caryologia. 2010. V. 63 (3). P. 292-303.
  203. Waje C.K., Jun S.Y., Lee Y.K., Moon K.D., Choi Y.H., Kwon J.H. Seed viability and functional properties of broccoli sprouts during germination and postharvest storage as affected by irradiation of seeds // J. Food Sci. 2009. V.74. P.C370-374.
  204. Wang L.J, Sheng M.Y., Wen P.C., Du J.Y. Morphological, physiological, cytological and phytochemical studies in diploid and colchicine-induced tetraploid plants of Fagopyrum tataricum (L.) Gaertn. // Bot. Stud. 2017. V.58(1):2.
  205. Wang M., Liu Y., Zhang C., Liu J., Liu X., Wang L. Wang W., Chen H., Wei C., Ye X., Li, X., Tu J. Gene editing by co-transformation of TALEN and chimeric RNA/DNA oligonucleotides on the rice OsEPSPS gene and the inheritance of mutations // PloS One. 2015. V.10 (4). e0122755.
  206. Wang Y., Cheng X., Shan Q., Zhang Y., Liu J., Gao C., Qiu J.L. Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew // Nat. Biotechnol. 2014. V. 32. P. 947–951.
  207. Warmke H.E. Experimental polyploidy and rubber content in Taraxacum kok-saghyz // Bot. Gaz. 1945. V.106. P.316-324.
  208. Watanabe K., Breier U., Hensel G., Kumlehn J., Schubert I., Reiss B. Stable gene replacement in barley by targeted double-strand break induction // Journal of experimental botany. 2015. V. 67 (5). P. 1433-1445.
  209. White F. Xanthomonas and the TAL effectors: Nature’s molecular biologist // TALENs: Methods and Protocols. 2016. V.1338. P. 1-8.
  210. Wolter F., Puchta H. Knocking out consumer concerns and regulator’s rules: efficient use of CRISPR/Cas ribonucleoprotein complexes for genome editing in cereals // Genome Biology. 2017. V. 18 (1). P. 43.
  211. Wright D.A., Thibodeau-Beganny S., Sander J.D., Winfrey R.J., Hirsh A.S., Eichtinger M., Fu F., Porteus M.H., Dobbs D., Voytas D.F., Joung J.K. Standardized reagents and protocols for engineering zinc finger nucleases by modular assembly // Nature Protocols. 2006. V. 1. P. 1637.
  212. Wright D.A., Townsend J.A., Winfrey R.J., Irwin P.A., Rajagopal J., Lonosky P.M., Hall B.D., Jondle M.D., Voytas D.F. High‐frequency homologous recombination in plants mediated by zinc‐finger nucleases // Plant Journal. 2005. V. 44. P. 693-705.
  213. Wu L., Yu Z. Radiobiological effects of a low-energy ion beam on wheat // Radiation and Environmental biophysics. 2001. V. 40 (1). P. 53-57.
  214. Wyvekens N., Topkar V.V., Khayter C., Joung J.K., Tsai S.Q. Dimeric CRISPR RNA-guided FokI-dCas9 nucleases directed by truncated gRNAs for highly specific genome editing // Hum. Gene Ther. 2015. V.26. P.425-431.
  215. Xiao A., Wu Y., Yang Z., Hu Y., Wang W., Zhang Y., Kong L., Gao G., Zhu Z., Lin S., Zhang B. EENdb: a database and knowledge base of ZFNs and TALENs for endonuclease engineering // Nucleic Acids Res. 2013. V.41. (Database issue). D415-422.
  216. Xu T., Bian N., Wen M., Xiao J., Yuan C., Cao A., Zhang S., Wang X., Wang H. Characterization of a common wheat (Triticum aestivum L.) high-tillering dwarf mutant // Theor. Appl. Genet. 2017. V.130. P.483-494.
  217. Yamamoto Y., Igawa T., Sumaoka J., Komiyama M. Hydrolysis of DNA by Ce (IV)/EDTA complexes—The mechanism of DNA cleavage and design of artificial restriction enzymes // Nucleic Acids Symposium Series. 2000. V. 44. P. 231-232.
  218. Yamamoto Y., Mori M., Tomita T., Zhou J.M., Komiyama M. Manipulation of double-stranded DNA by artificial restriction enzyme composed of Ce (IV)/EDTA and PNA // Nucleic Acids Symposium Series. 2004. V. 48. P. 279-280.
  219. Yamamoto Y., Uehara A., Tomita T., Komiyama M. Site-selective and hydrolytic two-strand scission of double-stranded DNA using Ce(IV)/EDTA and pseudo-complementary PNA // Nucleic Acids Res. 2004. V.32(19):e153.
  220. Yamamoto Y., Miura K., Komiyama M. Site-selective hydrolysis of huge DNA by artificial restriction DNA cutter // Nucleic Acids Symposium Series. 2006. V. 50. P. 265-266.
  221. Yamamoto Y., Uehara A., Miura K., Watanabe A., Aburatani H., Komiyama M. Development of artificial restriction DNA cutter composed of Ce(IV)/EDTA and PNA // Nucleosides Nucleotides Nucleic Acids. 2007. V.26. P.1265-1268.
  222. Yu Z., Deng J., He J., Huo Y., Wu Y., Wang X., Lui G. Mutation breeding by ion implantation // Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 1991. V. 59-60. P. 705-708.
  223. Zahedi A.A., Hosseini B., Fattahi M., Dehghan E., Parastar H., Madani H. Overproduction of valuable methoxylated flavones in induced tetraploid plants of Dracocephalum kotschyi Boiss // Bot. Stud. 2014. V.55(1):22.
  224. Zhang W., Liu X., Zheng F., Zeng S., Wu K., da Silva J.A.T., Duan J. Induction of rice mutations by high hydrostatic pressure // Plant Physiology and Biochemistry. 2013. V. 70. P. 182-187.
  225. Zhang X., Zhang X.F., Li H.P., Wang L.Y., Zhang C., Xing X.H., Bao C.Y. Atmospheric and room temperature plasma (ARTP) as a new powerful mutagenesis tool // Applied Microbiology and Biotechnology. 2014. V. 98. P. 5387-5396.
  226. Zhang Y., Zhang F., Li X., Baller J.A., Qi Y., Starker C.G., Bogdanove A.J. Voytas D.F. Transcription activator-like effector nucleases enable efficient plant genome engineering // Plant Physiology. 2013. V. 161. P. 20-27.
  227. Zhang J., Sumich A., Wang G.Y. Acute effects of radiofrequency electromagnetic field emitted by mobile phone on brain function // Bioelectromagnetics. 2017. V.38. P.329-338.
  228. Zhebrak A.R. Soviet biology // Science. 1945. V.102. P.357-358.
  229. Zhu T., Mettenburg K., Peterson D.J., Tagliani L., Baszczynski C.L. Engineering herbicide-resistant maize using chimeric RNA/DNA oligonucleotides // Nature Biotechnology. 2000. V. 18. P. 555-558.
  230. Zhu T., Peterson D.J., Tagliani L., Clair G.S., Baszczynski C.L., Bowen B. Targeted manipulation of maize genes in vivo using chimeric RNA/DNA oligonucleotides // Proceedings of the National Academy of Sciences. 1999. V. 96. P. 8768-8773.
Скачать pdf
наверх
eISSN: 2221-6197 DOI: 10.31301/2221-6197